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Symbol Name ID |
Stk17b
serine/threonine kinase 17b (apoptosis-inducing) MGI:2138162 |
| Darker colors indicate more annotations |
| Mouse Phenotypes | increased T cell proliferation |
decreased thymocyte number |
enlarged spleen |
increased spleen weight |
spleen hyperplasia |
decreased double-positive T cell number |
increased double-positive T cell number |
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number |
decreased CD4-positive, alpha-beta T cell number |
increased CD4-positive, alpha-beta T cell number |
decreased CD8-positive, alpha-beta T cell number |
increased memory T cell number |
decreased single-positive T cell number |
abnormal cytokine secretion |
increased interferon-gamma secretion |
increased interleukin-2 secretion |
increased tumor necrosis factor secretion |
decreased susceptibility to experimental autoimmune encephalomyelitis |
increased susceptibility to experimental autoimmune encephalomyelitis |
increased anti-nuclear antigen antibody level |
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| Availability | Mouse Genotype | ||||||||||||||||||||
| Stk17btm1Hed/Stk17btm1Hed | |||||||||||||||||||||
| Tg(Lck-Stk17b)26.1Wals/? | |||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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